Multiple data sources are available to AD-RCMAR Scientists and applicants, including:
| Name of Dataset | Study Aims | Population (N) | Variables |
| Hispanic Community Health Study/Study of Latinos (HCHS/SOL) | Multi-center epidemiologic study in Hispanic/Latino populations to assess role of acculturation in prevalence and development of disease and to identify factors affecting health. | 16,415 diverse Hispanics/Latinos | Neurocognitive,sociocultural (e.g., acculturation), cardiometabolic (e.g., ECG), and multilayered –omics (e.g., whole genome sequences) |
| Health and Retirement Study (HRS) | Longitudinal study of U.S. adults aged 50+ designed to inform retirement research | ~20,000, nationally representative | Multiple domains of health |
| Rancho Bernardo Study of Healthy Aging (RBS) | Community-based cohort study of adults from the Rancho Bernardo suburb of San Diego, CA focused on cardiovascular disease, diabetes, bone disease, and cognitive function | 2,500 predominantly Northern European-American and middle to upper-middle class | Multiple domains of health and health status including cognitive, physical, sensory, and pulmonary function, biomarkers, and imagin. |
| Health and Aging Brain Study-Health Disparities (HABS-HD) | The HABS-HD seeks to understand the biological, social and environmental factors that impact brain aging among diverse communities | 1,000 Mexican-Americans, 1,000 non-Hispanic Whites, and 1,000 African-Americans from North Texas | Neurocognitive testing, neuroimaging, and biomarkers |
| Hispanic – Established Populations for the Epidemiologic Study of the Elderly (H-EPESE) | Longitudinal study to provide estimates of physical health & mental health conditions, functional impairment and to compare to other populations | 3,050 Mexican-Americans aged 65+ years (8 waves of data) with an additional sample of 75+ years in wave 5. | Multiple domains of physical, mental health, cognition, functional status, sociodemographics |
| Alzheimer’s Disease Cooperative Study (ADCS) | AD Clinical Trials addressing treatments for cognitive and behavioral symptoms | 6,500 people and 25,000 samples | Biospecimens, brain imaging data, biochemical biomarkers, medications, MMSE, ADAS-cog, Clinical Dementia Rating Scale, Neuropsychiatric Inventory, CSF and serum data |
| UCSD Shiley-Marcos ADRC Clinical Core Database | Multiple studies aiming to understand the causes, clinical features and treatments for MCI and ADRD | Over 3,500 older adults, including 17% Latinos | Multiple variables, including MINT, arterial stiffness, caregiver stress, medical, neurological and neuropsychological data, MRI, CSF data and quantitative MR brain imaging |
| National Alzheimer’s Coordinating Center (NACC) | Facilitates collaborative research on ADRD | 35,000+ older adults | National standard clinical and neuropathological data (prospective and longitudinal) (Uniform Data Set, Neuropathology Data Set, Minimum Data Set) |
| All of Us Research Program | All of Us is building a diverse database that can inform thousands of studies on a variety of health conditions | 1,000,000 racially diverse people across the US | EHR data, genomics, physical measurements and wearables, personal history, lifestyle, healthcare access and utilization, social determinants of health |
| Successful Aging Evaluation (SAGE) | Aims to investigate what factors (emotional, cognitive, genetic, social, physical, etc.) are associated with successful aging across the lifespan | 1,800 randomly selected, demographically representative, older adult residents of San Diego, CA | Broad range of topics related to successful aging assessed by questionnaire, as well as genetic data |
